Always depends on the situation, as in position, chip stacks and the players in the hand. Against a tight aggressive player it often works (if OOP) to make a standard c-bet. If I get a call, I'll check the turn trying to induce either a bluff or a bet if he does have a hand and go for a check-raise. Against a calling station, who cares... just keep firing.
Limit poker is a science, but no-limit is an art. In limit you are shooting at a target. In no-limit, the target comes alive and shoots back at you.
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